Composition
- Each roll on contains:
- Diclofenac diethyl amine BP 1.16 % W/W
- Linseed Oil BP
3.0 % W/W
- Methyl Salicylate IP
10.0% W/W
- Menthol IP
0.5 % W/W
- Benzyl Alcohol
IP 1% W/V
Packing
- 40 gm
MRP
- 98
Overview
This combination is used to relieve the joint pain, stiffness, swelling in arthritis.
Indications
- Rheumatoid arthritis
- Sprain & strain
About Composition
Diclofenac Diethylamine:
diclofenac is phenyl acetic acid derivative and non -steroidal anti -inflammatory drug Diclofenac inhibit cox -1 and cox-2 enzyme and prevents the synthesis of prostaglandinsLinseed oil:
Linseed oil is known by name flaxseed oil. It is rich in ALA which helps reduction of joint of inflammationMethyl salicylate:
It is the methyl ester of the salicylic acid. It is topically used to provide relief against joint pain caused strains, sprains and arthritis. Methyl salicylate is known as counter irritant.Menthol:
menthol provides cooling sensation and act as counter irritant. It acts as the activator of the transient receptor potential melastatin compound.Benzyl Alcohol:
Benzyl alcohol has local anaesthetic activity and relieves the superficial skin pain and also has preservative action.Mechanism of action
Diclofenac Diethylamine:
diclofenac is phenyl acetic acid derivative and non -steroidal anti -inflammatory drug Diclofenac inhibit cox -1 and cox-2 enzyme and prevents the synthesis of prostaglandinsMethyl salicylate:
it works by causing the skin to feel cool and warm this helps in reducing pain of joints, muscles and tendonsMenthol:
it works by imparting the cooling effect by activating nociceptors and desensitize that receptors and reduces painLinseed oil:
flaxseed oil is the source of the polyunsaturated fatty acids. It contains alpha- linolenic acid that decreases the inflammation so therefore it is useful in the rheumatoid arthritis and other inflammatory diseases.Contraindications
- Contraindicated in people with known allergy
- Contraindicated in people with increase chances of bleeding
Side Effects
- Itching
- Increased swelling
- Dryness
- Blistering of the skin
- Allergic reactions